Cytoscape

Project Website: http://www.cytoscape.org

Cytoscape is an open-source bioinformatics software platform for visualizing molecular interaction networks and biological pathways, and integrating these networks with annotations, gene expression profiles, and other state data. Cytoscape core distribution provides a basic set of features for data integration and visualization. Additional features are available as plugins.

Cytoscape is a Java-based application that downloads to your local machine when you launch it from GenomeSpace. Once it's downloaded to your machine (after a launch from GenomeSpace), you can start it locally (by opening the JNLP) or launch from GenomeSpace. If you launch Cytoscape from the Cytoscape website, at this time it will not be the version that is linked to GenomeSpace.

Like several other applications in the GenomeSpace suite of tools, Cytoscape can be expanded with plug-ins. You can download plug-ins for your Cytoscape by choosing Plugins>Manage Plugins.

Cytoscape has several GenomeSpace menu items.

Logging In

When you launch Cytoscape from GenomeSpace, your login should be handled seamlessly.

If you start from your GenomeSpace-enabled JNLP of Cytoscape and want to log into GenomeSpace in order to access your Amazon cloud storage or other GenomeSpace tools, you will be asked to log in with your GenomeSpace username and password.

You can also Reset Password on your existing GenomeSpace account.

Import Menu

Clicking File>Import>GenomeSpace provides several options for importing files from GenomeSpace.

Load Network	Loads a network from your GenomeSpace cloud storage.
Load Network from Table	Starts the import from your GenomeSpace cloud storage of a network from a delimited text file or single-sheet MS Excel workbook.
Load Attributes	Loads attributes (for node/edge/network) from your GenomeSpace cloud storage. The load dialog allows you to opt to either Load node attributes or Load edge attributes.
Load CyTable	Loads a file containing attributes for a CyNetwork from your GenomeSpace cloud storage. The load dialog allows you to opt to either Load node attributes or Load edge attributes.
Load Attributes from Table	Starts the import from your GenomeSpace cloud storage of delimited text or single-sheet MS Excel workbook containing attribute data tables that are not formatted into Cytoscape node or edge attribute file formats.
Load Session	Loads a CYS file from your GenomeSpace cloud storage. A session file (CYS) contains all networks, attributes (for node/edge/network), Desktop states (selected/hidden nodes and edges, window sizes), Properties, some plugin states, and Visual Styles present in a given working state.
Load Ontology and Annotations	Loads an annotation/ontology file from your GenomeSpace cloud storage. Annotations in Cytoscape are stored as a set of ontologies (a set of controlled vocabulary terms that annotate the objects).The standard file formats used in Cytoscape are OBO and Gene Association.

Export Menu

Clicking File>Export>GenomeSpace provides options for exporting files to GenomeSpace.

Upload File	Uploads a file from your local machine to the root level of your GenomeSpace cloud storage.
Save Session As	Saves a session file (CYS), containing all networks, attributes (for node/edge/network), Desktop states (selected/hidden nodes and edges, window sizes), Properties, some plugin states, and Visual Styles in your present working state to your GenomeSpace cloud storage.
Save Network As	Save a network to your GenomeSpace cloud storage.

GenomeSpace Menu

Clicking File>GenomeSpace provides several options for managing your files in your GenomeSpace cloud storage and using GenomeSpace to launch other applications.

Delete File in GenomeSpace	Delete a file from your GenomeSpace cloud storage.
Download File	Download a file in your GenomeSpace cloud storage to your local machine.
List Available Files in GenomeSpace	Navigate your GenomeSpace directories.
Login To GenomeSpace	Log into your GenomeSpace account.
Launch	Launch another GenomeSpace tool

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